|
KMID : 1007320170230020131
|
|
Journal of the Korean Society of Menopause
2017 Volume.23 No. 2 p.131 ~ p.134
|
|
|
Metachronous Cancer of Breast and Adenocarcinoma of Cervix: A Rare Case Report
|
|
Sharma Nalini
Lalnunnem Thiek J.
Rituparna Das
Mishra Jaya
Singh Ahanthem Santa
|
|
|
Abstract
|
|
|
|
The occurrence of a second primary cancer in a cancer survivor is well documented. It may be synchronous or metachronous. Incidence of metachronous cancer involving cervix is 0.82% to 1.33%. One such metachronous cancer is that of breast and cervix. We present a case of a woman who received tamoxifen for invasive ductal cancer of breast following a modified radical mastectomy and subsequently developed adenocarcinoma of cervix after six month of tamoxifen therapy. The role of tamoxifen in pathogenesis of cervical cancer and that of human papillomavirus infection in pathogenesis of both cancer of cervix and breast cancer has been well recognized. In our patient, the adenocarcinoma of cervix (rare occurrence) which is likely due to six month of tamoxifen therapy is a perplexing question. Women diagnosed and treated for breast cancer need to be followed up for development of other metachronous gynecological cancers. (J Menopausal Med 2017;23:131-134)
|
|
|
KEYWORD
|
|
|
Cervical cancer , Metachronous cancer , Tamoxifen Breast cancer
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|